NOA can occur for a variety of reasons:Hormonal imbalances: A disorder like NOA might be brought on by a hormonal deficit,issues with the genes and chromosomes.Testicular failure occurs when there is insufficient generation of sperm because there are insufficient germ cells in the testes.Maturation arrest is the absence of the final stages of the biological process known as spermatogenesis, which produces mature, motile sperm cells from early-stage cells.

Non-Obstructive Azoospermia is a condition in which a male is unable to produce sperm. The couple cannot conceive naturally as a result. The ICSI procedure allows doctors to remove healthy sperm from the testicles and utilise them to fertilise the egg following a combination of effective medical and surgical procedures.

The primary test for diagnosis is sperm analysis. In azoospermia, no sperm are present.To determine the causes and establish a treatment plan, additional investigations such hormone tests, chromosomal analysis (Karyotype and Yq microdeletions), and testicular ultrasonography are helpful.

NOA is treated with a combination of surgical intervention and medication, including hormone therapy. The surgical methods for removing sperm from the testes directly are called TESE and Micro-TESE. ICSI fertility treatments will assist the couple in fertilising the eggs and obtaining the embryos once the sperm have been located.