It is unclear what specifically causes autoimmune disorders. Some persons are thought to have a genetic predisposition toward autoimmunity. Infections brought on by specific bacteria or viruses are another cause or condition that might set off autoimmune disorders. Additionally, some substances including irritants in the environment and chemicals might cause autoimmunity.

Ovaries, endometrium, and testes are among the reproductive organs that can be impacted by autoimmune diseases in both men and women. Ovarian reserve, or the quantity and quality of eggs at any given age, can be prematurely diminished in women with autoimmune diseases that affect the ovaries. As a result, it might reduce such women's reproductive potential. Similar to this, men's sperm counts occasionally drop.Reduced fertility is a common effect of autoimmune diseases, such as diabetes, autoimmune thyroid disease, systemic lupus erythematosus, etc.

There are no known specific treatments for the numerous symptoms that are caused by autoimmune disorders. For the best results, it is crucial that the autoimmune illness be correctly diagnosed, well-managed, and stable prior to fertility therapy. People with autoimmune diseases can get expert advice from a fertility specialist and a rheumatologist to help them through the process of trying to get pregnant.

The immune system may attack and harm the body's own organs, including the reproductive system, as a result of autoimmune illnesses. This may make it harder to get pregnant. Your chances of having a successful therapy and becoming pregnant will increase with prompt diagnosis and care prior to fertility treatments